Products are packed and if necessary repacked with utmost care and precaution, the purpose is to minimize shipment volume and discretion. Our organization name or anything else that would imply pharmaceutical contents of the package is never used in our shipments. The size of our packages is never larger than what would cause unnecessary suspicion. If the order is too large to fit one of these packages, the order will automatically be divided into two or more packages (always included in the S&H-charges). Shipments are made from various shipping points in different European countries.
In the absence of androgen, all known antiandrogens cause translocation of AR from the cytoplasm to the nucleus,    whereas EPI-001 does not cause the AR to become nuclear.  Binding of EPI-001 to the NTD of the AR blocks protein-protein interactions that are essential for its transcriptional activity. Specifically, EPI-001 blocks AR interactions with CREB-binding protein , RAP74 , and between the NTD and C-terminal domain (termed N/C interaction) required for antiparallel dimer formation of AR.  Unlike antiandrogens such as bicalutamide,   EPI-001 does not cause the AR to bind to androgen response elements on the DNA of target genes.